In accordance with regulatory guidelines, certain treatment names on this site have been replaced with generic terms. Ask us during your consultation for details.

Polynucleotide (PN) Injections

Polynucleotide (PDRN/PN) injections that repair skin at the cellular level for improved texture, hydration, and elasticity

In accordance with Singapore's healthcare advertising guidelines, we are unable to list specific product or device brand names on this website. All descriptions use approved generic terminology. To find out which products are used at VE Aesthetic Clinic, chat with us on WhatsApp or ask us during your consultation.

Face · Skin Treatment

Repair from Within

Polynucleotide (PN) injections are a skin healing treatment derived from salmon DNA (polydeoxyribonucleotide, PDRN). It works by activating the skin's own repair mechanisms, stimulating fibroblasts to produce new collagen and restore healthy skin function.

Unlike conventional moisturising or volumising treatments, polynucleotide therapy addresses skin at a biological level, improving texture, reducing fine lines, restoring elasticity, and enhancing overall skin health over time.

Polynucleotide (PN) Injections

What It Treats

Cheeks & Facial Skin Quality

Improve overall skin texture and hydration across the face with polynucleotide repair.

Under-Eye Rejuvenation (PN Eye Formula)

A specialised formula for delicate under-eye skin to improve dark circles and thin skin.

Perioral Lines & Lips

Improve lip skin texture, reduce fine lines around the mouth, and enhance lip hydration.

Dry & Dehydrated Skin

Restore the moisture barrier and skin health from within for a sustained dewy glow.

Wrinkles & Fine Lines

Rebuild the skin's repair mechanism to smooth fine lines and improve elasticity.

How It Works

01

PDRN cell activation

Polydeoxyribonucleotide fragments bind to receptors on skin cells, triggering a signalling cascade that activates growth factors, reduces inflammation, and stimulates collagen-producing cells to regenerate the skin.

02

Fibroblast stimulation

Polynucleotide therapy activates fibroblasts, the cells responsible for producing collagen, elastin, and hyaluronic acid, leading to gradual structural improvement in the skin.

03

Anti-inflammatory effect

PDRN has documented anti-inflammatory properties, making polynucleotide treatment particularly effective for damaged, reactive, and post-acne skin.

04

Progressive skin healing

Improvements are cumulative and continue for weeks after each session. A course of 3-4 treatments spaced 3-4 weeks apart is typically recommended for best results.

What to Expect

The Procedure

Sessions take 30 to 45 minutes. Topical numbing cream is applied beforehand. Multiple micro-injections are made across the treatment area using a fine needle. Most customers describe mild stinging or pressure at each injection point.

Downtime

Minimal. Small red pinpoint marks may be visible for a few hours. Mild swelling at injection sites typically resolves within 1 to 2 days. Most customers return to normal activities the same day.

Results & Longevity

Subtle improvement is visible after each session, with the cumulative benefit most apparent after a course of 3 to 4 sessions spaced 3 to 4 weeks apart. Improvements continue for weeks after the final session as cellular repair progresses.

Frequently Asked Questions

Find Out If This Is Right for You

Treatments at VE Aesthetic Clinic are recommended only after a thorough consultation. Our doctor will assess your concerns and advise whether this treatment suits your goals and skin type.